- Atrial fibrillation
- Mitral annular calcification (moderate or greater)
- Mitral stenosis (any) or mitral regurgitation (moderate or greater)
- Mitral valve repair or prosthetic mitral valve
- Left bundle branch block or ventricular paced rhythm
Diastole is made off four phases
- Isovolumetric relaxation time or IVRT (end of AV flow to rapid early filling)
- Passive filling (E-Wave)
- Diastasis (end of passive filling, equalization of pressure in LV and LA)
- Atrial Contraction (A-wave)
- We can visualize this with echo using a PW doppler just above the MV leaflets in the Apical 4 Chamber
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Diastolic dysfunction: generally caused by impaired LV relaxation, reduced restoring forces, and increased LV thickness
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Elevated LV Filling Pressures (pressures in the left ventricle during diastole) without increased volumes is suggestive of diastolic dysfunction.
- Mitral Inflow PW Doppler (Example)
- Measure just above mitral valve leaflets in apical four chamber
- E-wave velocity:
- A-wave velocity:
- E/A ratio:
- Medial Mitral Annulus PW TDI (Example)
- e’ velocity:
- TR Systolic Jet Velocity (Example)
- Parasternal or apical 4 chamber highest velocity CW Doppler of TR jet
- LA Volume Index (Example)
- Calculate biplane volumes by measuring LA in apical 4 chamber and apical 2 chamber then index to BSA
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- Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. European heart journal cardiovascular Imaging. 2016; 17(12):1321-1360.
- https://www.123sonography.com/diastolic-function-and-diastolic-dysfunction
- Aurigemma GP, Gaasch WH. Diastolic Heart Failure N Engl J Med. 2004; 351(11):1097-1105.